“Executive Order "Launching the Genesis Mission": "Within 60 days of the date of this order, the Secretary [of Energy] shall identify and submit to the APST a detailed list of at least 20 science and technology challenges of national importance that the Secretary assesses to have potential to be addressed through the Mission."”

Donald TrumpPolicymaker

President of the United States

DOE identified 26 Genesis Mission National Science and Technology Challenges — exceeding the 20 minimum — which were published on February 12, 2026 following the APST's 30-day review window, timing consistent with an on-time submission (the exact internal submission date to the APST was not made public).